Hydrogel based drug delivery system: A review

نویسندگان

چکیده

Hydrogels are the three-dimensional hydrophilic network which is crosslinked physically or chemically. also called as gels because they absorb considerate amount of water. The characteristic properties hydrogels swelling, mechanical properties, biodegradable, elasticity, biocompatible, easy to modify, flexibility, etc. They classified based on source, polymeric composition, biodegradability, configuration, cross linking, physical appearance, chemical charges, and drug release. can be synthesized from natural, synthetic, semisynthetic polymers via physical, crosslinking, through grafting, coacervation polymerization. useful in daily life their major applications delivery oral cavity, GI tract, rectal, ocular, protein, subcutaneous, transdermal, controlled delivery, preparation contact lenses, wound healing, tissue engineering, biosensing, bacterial culture preparation, various other fields like agriculture, electronics, cosmetics, gene perfume regenerative medicine, plastic surgery, sealant adhesive, watering beads for plant water purification.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Review: Chitosan Based Hydrogel Polymeric Beads – as Drug Delivery System

Chitosan obtained by alkaline deacetylation of chitin is a non-toxic, biocompatible, and biodegradable natural polymer. Chitosan-based hydrogel polymeric beads have been extensively studied as microor nano-particulate carriers in the pharmaceutical and medical fields, where they have shown promise for drug delivery as a result of their controlled and sustained release properties, as well as bio...

متن کامل

Design a Biodegradable Hydrogel for Drug Delivery System

In this article, we synthesize a novel chitosan -based superabsorbent hydrogel via graft copolymerization of mixtures acrylic acid (AA) and N-vinyl pyrollidon onto chitosan backbones. The polymerization reaction was carried out in an aqueous medium and in the presence of ammonium persulfate (APS) as an initiator and N,N'-methylene bisacrylamide (MBA) as a crosslinker.The hydrogel structures wer...

متن کامل

Formulation Development and Evaluation of Hydrogel Based Gastroretentive Drug Delivery System of Antihypertensive Drug

Site specific drug delivery has become the important aspect of research. In present study focused has been made to formulate gastroretentive drug delivery (GRDDS) of drugs having narrow absorption window or having good absorption at proximal part of gastrointestinal tract (GIT) to deliver at stomach site. Hydrogel based gastroretentive formulation of ramipril were prepared by gas blowing techni...

متن کامل

Magnetic/pH-sensitive nanocomposite hydrogel based carboxymethyl cellulose –g- polyacrylamide/montmorillonite for colon targeted drug delivery

Objective(s): The main aim of current research was to develop a novel magnetically responsive hydrogel by radical polymerization of carboxymethyl cellulose (CMC) on acryl amide (Am) using N,N'-methylene bis acrylamide  (MBA)  as a crosslinking agent, potassium persulfate (KPS) as a free radical initiator, and  magnetic montmorillonite ( mMT)  nanoclay as nano-...

متن کامل

Recent Advances in Hydrogel-Based Drug Delivery for Melanoma Cancer Therapy: A Mini Review

The purpose of this study is to describe some of the latest advances in using hydrogels for cancer melanoma therapy. Hydrogel formulations of polymeric material from natural or synthetic sources combined with therapeutic agents have gained great attention in the recent years for treating various maladies. These formulations can be categorized according to the strategies that induce cancer cell ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: World Journal of Biology Pharmacy and Health Sciences

سال: 2022

ISSN: ['2582-5542']

DOI: https://doi.org/10.30574/wjbphs.2022.12.3.0227